Pizza Mac and Cheese Bake

Ultimate Macaroni and Cheese Pizza Casserole: A Family-Friendly Fusion Feast

Delicious Macaroni and Cheese Pizza Casserole baked to perfection, showcasing golden cheese and pepperoni
Close-up of bubbling Macaroni and Cheese Pizza Casserole with visible pepperoni and melted cheese
A perfectly portioned slice of Macaroni and Cheese Pizza Casserole on a white plate
Top-down view of the freshly baked Macaroni and Cheese Pizza Casserole in a baking dish, ready to be served

Prepare to delight your taste buds with a culinary creation that brings together two of America’s most beloved comfort foods: creamy macaroni and cheese and savory pizza. This Macaroni and Cheese Pizza Casserole is an ingenious dish that promises to be a showstopper at any dinner table, particularly appealing to families and kids alike. It’s the ultimate fusion, delivering the rich, cheesy goodness of mac and cheese with the exciting flavors and toppings of a classic pepperoni pizza, all baked together in one easy-to-make casserole.

Forget the dilemma of choosing between pasta night and pizza night. With this recipe, you get the best of both worlds in a single, satisfying meal. It’s perfect for busy weeknights when you need a hearty, delicious, and fuss-free dinner that doesn’t compromise on flavor. The simplicity of using boxed macaroni and cheese as a base makes this recipe incredibly approachable, even for novice cooks, while the added fresh vegetables and flavorful Italian sausage elevate it to a gourmet experience that belies its humble beginnings.

This casserole is not just about convenience; it’s about creating a memorable meal that everyone will ask for again and again. Its bubbling cheese topping, perfectly cooked pasta, and savory meat with vibrant bell peppers create a symphony of textures and flavors. Each bite offers a harmonious blend of creamy, tangy, and savory notes, reminiscent of your favorite pizza parlor but with the heartwarming essence of a homemade casserole. Whether you’re hosting a casual get-together, feeding a hungry family, or simply craving something uniquely comforting, this Macaroni and Cheese Pizza Casserole is your go-to recipe for a delicious and easy meal.

Why This Macaroni and Cheese Pizza Casserole Will Become Your New Favorite

There are countless reasons why this particular casserole stands out and why it will quickly earn a permanent spot in your recipe rotation. It’s more than just a meal; it’s a delightful experience that simplifies dinner preparation while maximizing flavor and satisfaction. Here’s what makes it truly special and why families everywhere are falling in love with this creative combination:

  • Kid-Friendly & Crowd-Pleasing: If you have picky eaters, this dish is a dream come true. The familiar, comforting flavors of mac and cheese combined with the exciting and universally loved appeal of pizza toppings make it an instant hit with children. Adults will equally appreciate the nostalgic comfort and the surprisingly sophisticated blend of ingredients. It’s truly a dish that bridges generational culinary preferences.
  • Incredibly Easy to Make: With straightforward steps and readily available, common ingredients, this recipe requires minimal effort and cooking expertise. Even on your busiest days, you can whip up this casserole without feeling overwhelmed. The smart use of boxed mac and cheese as a foundation significantly cuts down on prep time, making it accessible for everyone.
  • Highly Customizable: While the recipe provides a fantastic and foolproof foundation, it’s also incredibly versatile. You can easily adapt it to suit your family’s specific preferences, dietary needs, or simply whatever ingredients you happen to have on hand. Think beyond pepperoni and bell peppers – the possibilities for customization are endless, from different meats to various vegetables and cheese blends!
  • Perfect for Weeknights: Looking for a hearty, filling, and comforting meal that comes together quickly after a long day? This casserole fits the bill perfectly. With a hands-on prep time of just 15 minutes and a cook time of 30-35 minutes, a delicious, homemade dinner can be on the table in under an hour, allowing more time for family and relaxation.
  • Comfort Food at Its Best: There’s something inherently comforting and deeply satisfying about a warm, bubbling, cheesy casserole. This dish takes that comfort to the next level by expertly merging two classic comfort foods into one irresistible creation, offering a double dose of warmth and nostalgia.
  • Great for Leftovers: Should you be fortunate enough to have any leftovers, they reheat beautifully, making this an excellent option for meal prepping throughout the week or packing delicious lunches for the next day. The flavors often meld and deepen overnight, sometimes tasting even better on day two!

Essential Ingredients for Your Pizza Mac and Cheese

Crafting this incredible casserole starts with a selection of simple yet powerful ingredients that come together to create a harmonious blend of flavors and textures. Each component plays a vital role in achieving that perfect pizza mac and cheese experience. Sourcing quality ingredients, even for a quick meal like this, can make a noticeable difference in the final taste and enjoyment. Here’s a closer look at what you’ll need to create this culinary masterpiece:

  • Green and Yellow Bell Peppers: These vibrant vegetables add a wonderful crunch, a subtle sweetness, and a much-needed burst of color to the casserole. Dicing them ensures they cook evenly and integrate well with the other ingredients, providing texture without being overpowering. Feel free to use red or orange bell peppers as well for even more color and a slightly sweeter flavor profile.
  • Italian Sausage: The star protein of this dish, Italian sausage, brings a rich, savory, and often slightly spicy depth that perfectly complements the creamy pasta and zesty pizza sauce. You have the flexibility to choose mild, medium, or hot Italian sausage based on your preference for heat. If Italian sausage isn’t available or preferred, ground beef, ground turkey, or even a plant-based ground meat substitute can also be used effectively.
  • Boxed Macaroni and Cheese: The ultimate shortcut for achieving that classic creamy base! Using a 7.25 oz box of Kraft macaroni and cheese (or your favorite brand) significantly saves time and guarantees that familiar, comforting cheesy flavor. It’s crucial to remember a key step here: save the cheese powder packet that comes with the boxed macaroni and cheese; it’s essential for infusing our casserole with its signature cheesy essence later on.
  • Pizza Sauce: A good quality pizza sauce is paramount to achieving that authentic pizza flavor that ties the whole dish together. A 14 oz can or jar of your favorite marinara or pizza sauce will work wonderfully. Opt for a brand with a robust, slightly tangy tomato flavor for the best results, as this will be a dominant flavor in the casserole.
  • Sliced Pepperoni: No pizza casserole would be truly complete without the iconic pepperoni! These classic savory, slightly spicy discs add a fantastic layer of flavor, a pleasing chewiness, and an instantly recognizable pizza aesthetic. About 20-25 slices are perfect for layering generously on top, creating that traditional pizza look and a burst of salty, smoky goodness in every bite.
  • Mozzarella Cheese: For that irresistible, gooey, stretchy top layer that we all love in a casserole, shredded mozzarella cheese is an absolute must. It melts beautifully to form a golden, bubbly crust that ties all the individual flavors and textures together into a cohesive and delicious whole. Feel free to mix in a bit of provolone or shredded white cheddar for added complexity and a different melt consistency.

Beyond these core ingredients, you’ll also need nonstick cooking spray for your baking dish, ensuring a smooth removal of your delicious casserole once baked. The true beauty of this recipe lies not just in its simplicity, but in the magical ability of these common, accessible ingredients to transform into something extraordinary and profoundly satisfying.

Macaroni and Cheese Pizza Casserole ready to bake with cheese and pepperoni on top

4.46 from 11 votes

Macaroni and Cheese Pizza Casserole

By: Julia Pacheco
Macaroni and cheese pizza casserole combines two favorites—cheesy pasta and pizza toppings—in one easy, kid-approved dish.
Prep: 15 minutes
Cook: 30 minutes
Total: 45 minutes
Servings: 6 servings
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Ingredients 

  • 1 green bell pepper, diced
  • 1 yellow bell pepper, diced
  • 1 lb Italian sausage
  • 1 – 7.25 oz box Kraft macaroni and cheese
  • 14 oz pizza sauce
  • 20-25 sliced pepperonis
  • ¾ cup Mozzarella cheese
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Instructions 

  • Preheat oven to 350 degrees F.
  • To a medium pot of boiling water on the stove add in the box of macaroni (save the cheese packet for later) and boil for 7 minutes or until the pasta is tender. Drain and set to the side.
  • To a large skillet over medium heat add the diced pepper, onion and sausage break the sausage up and cook it through. Remove any grease in the pan then add in the cooked macaroni noodles, cheese packet and pizza sauce stir well. Spray a 9 x 13 baking dish with nonstick spray then add this casserole mixture in there. Top with the pepperonis and mozzarella cheese. Bake for 30 to 35 minutes. Enjoy!

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Nutrition

Calories: 378kcal | Carbohydrates: 9g | Protein: 17g | Fat: 31g | Saturated Fat: 12g | Polyunsaturated Fat: 4g | Monounsaturated Fat: 13g | Trans Fat: 0.1g | Cholesterol: 75mg | Sodium: 1096mg | Potassium: 503mg | Fiber: 2g | Sugar: 3g | Vitamin A: 494IU | Vitamin C: 58mg | Calcium: 106mg | Iron: 2mg

Nutrition information is automatically calculated, so should only be used as an approximation.

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Step-by-Step Guide: Crafting Your Pizza Mac and Cheese

Creating this Macaroni and Cheese Pizza Casserole is a straightforward process, broken down into a few simple steps. Follow these detailed instructions carefully to ensure your casserole turns out perfectly every time, delivering maximum flavor and minimal fuss. Precision in each step guarantees a delicious and satisfying result.

  1. Preheat Your Oven: Begin by preheating your oven to 350 degrees F (175 degrees C). This essential first step ensures the oven is at the correct, consistent temperature when your casserole is ready to bake, which is crucial for even cooking and achieving that beautifully golden-brown, bubbly top.
  2. Cook the Macaroni: In a medium-sized pot, bring a generous amount of salted water to a rolling boil on the stovetop. Add the macaroni from the box of Kraft macaroni and cheese to the boiling water. Cook for approximately 7 minutes, or until the pasta is tender but still retains a slight bite (al dente). It’s important not to overcook the pasta at this stage, as it will continue to cook and absorb flavors when baked in the oven. Once cooked, thoroughly drain the macaroni and set it aside. Crucially, remember to save the cheese powder packet that comes with the boxed macaroni and cheese; we’ll incorporate it later to infuse that signature cheesy flavor directly into our casserole mixture.
  3. Prepare the Sausage and Vegetables: While the macaroni is cooking, heat a large, heavy-bottomed skillet over medium heat. Add the diced green and yellow bell peppers along with the Italian sausage to the hot skillet. Using a spoon or spatula, break the sausage into smaller, bite-sized pieces as it cooks. Sauté the mixture until the sausage is thoroughly browned and cooked through, and the bell peppers have softened slightly, developing a tender-crisp texture. Once cooked, carefully drain any excess grease from the skillet to prevent your casserole from becoming overly oily, ensuring a more palatable and lighter texture.
  4. Combine the Casserole Base: Return the skillet (with the cooked sausage and bell peppers) to the stove if you removed it. Add the drained macaroni noodles, the reserved cheese powder packet from the boxed mac and cheese, and the pizza sauce directly into the skillet. Stir all the ingredients together thoroughly and gently, ensuring that the macaroni is well coated with the savory sauce and rich cheese powder, and that the sausage and vegetables are evenly distributed throughout the mixture. This combination forms the hearty and flavorful base of your casserole.
  5. Assemble and Top: Lightly spray a 9×13 inch baking dish with nonstick cooking spray to prevent sticking. Carefully transfer the macaroni, sausage, and pizza mixture into the prepared baking dish, spreading it out evenly across the bottom. Next, artfully arrange the sliced pepperonis over the top of the casserole in a single layer, ensuring good coverage for that classic pizza look and flavor in every bite. Finally, sprinkle the mozzarella cheese generously and evenly over the pepperonis. This will create a mouth-watering, bubbly, and beautifully melted cheese layer during baking.
  6. Bake to Perfection: Place the assembled baking dish into your preheated oven. Bake for approximately 30 to 35 minutes. You’ll know it’s ready when the cheese on top is completely melted, beautifully bubbly, and has developed a light golden-brown color, and the casserole is heated through to the center.
  7. Serve and Enjoy: Carefully remove the hot casserole from the oven. It’s advisable to allow it to rest for a few minutes (about 5-10 minutes) before serving. This brief resting period helps the cheese set slightly and allows the flavors to meld, making it easier to cut into neat, delicious portions. Cut into generous squares or scoops and serve immediately to enjoy your spectacular Macaroni and Cheese Pizza Casserole!

Tips for Success & Common Questions

Even though this recipe is designed for ease and simplicity, a few expert tips can ensure your Macaroni and Cheese Pizza Casserole turns out spectacular every single time. And to address any lingering doubts or curiosity, here are answers to some common questions that often arise with this delightful dish:

Pro Tips for the Perfect Casserole:

  • Don’t Overcook the Macaroni: As mentioned in the instructions, the pasta will continue to cook and soften in the oven. Boiling it slightly less than the package directions (around 7 minutes, or until it’s just al dente) will result in a perfectly tender texture in the final casserole, preventing it from becoming mushy or overcooked.
  • Thoroughly Drain Sausage Fat: Italian sausage, especially some varieties, can release a fair amount of grease during cooking. Draining this fat thoroughly after browning is crucial for a cleaner, less greasy, and more flavorful casserole, allowing the rich taste of the meat and other ingredients to shine through without being masked by excess oil.
  • Customize Your Toppings and Seasoning: Think of this casserole as a delicious blank canvas for your culinary imagination! For an enhanced pizza flavor, consider stirring a pinch of Italian seasoning into the macaroni mixture, or sprinkle some dried oregano, basil, or a mix of Italian herbs on top of the mozzarella cheese before baking. A light dusting of garlic powder can also add a subtle depth.
  • Ensure Evenly Spread Ingredients: When combining the macaroni mixture and spreading it into your baking dish, take an extra moment to ensure all ingredients are distributed as evenly as possible. This meticulous step guarantees that every single bite of your casserole is packed with all the delicious components – macaroni, sausage, peppers, and sauce – creating a consistent and satisfying experience.

Frequently Asked Questions:

Can I use different pasta shapes for this casserole?
Absolutely! While elbow macaroni is the classic choice for mac and cheese, other small to medium pasta shapes would also work wonderfully. Consider ditalini, small shells, rotini, or cavatappi. Just ensure that whichever shape you choose, it is cooked al dente (slightly undercooked) before mixing it into the casserole, as it will continue to cook in the oven.
What other proteins can I use if I don’t have Italian sausage?
There are several great alternatives! Cooked and crumbled ground beef, ground turkey, cooked shredded chicken (rotisserie chicken works great!), or even diced ham are excellent substitutes for Italian sausage. For a vegetarian option, consider sautéed mushrooms, black beans, chickpeas, or a plant-based ground meat substitute to add substance and flavor.
How can I make this Macaroni and Cheese Pizza Casserole spicier?
To introduce a delightful kick, you have a few options: opt for hot Italian sausage instead of mild, add a generous pinch or two of red pepper flakes to the sausage and veggie mixture while it cooks, or for a bolder heat, top the casserole with sliced jalapeños or banana peppers before baking.
Can I prepare this casserole ahead of time?
Yes, this casserole is an excellent candidate for make-ahead meal prep! You can assemble the entire casserole (without baking it) and cover it tightly with aluminum foil or plastic wrap. Refrigerate it for up to 24 hours. When you’re ready to bake, you might need to add an extra 5-10 minutes to the baking time to ensure it heats through completely from the chilled state.
How do I store and reheat leftovers effectively?
To store any leftover casserole, transfer it to an airtight container and keep it in the refrigerator for up to 3-4 days. For reheating, individual portions can be easily warmed in the microwave until hot. If reheating a larger portion or the entire casserole, cover the dish with foil and reheat in the oven at 300°F (150°C) until thoroughly warmed through to prevent drying out.

Variations to Unleash Your Inner Chef

One of the most exciting aspects of the Macaroni and Cheese Pizza Casserole is its incredible adaptability. This recipe is a fantastic starting point, but don’t be afraid to experiment and make it truly your own! By swapping out or adding ingredients, you can cater to different tastes, utilize what you have on hand, and create a unique culinary experience. Here are some exciting variations to inspire your culinary creativity:

  • Meat Lover’s Dream: For those who can’t get enough meat, elevate this casserole by adding more proteins. In addition to Italian sausage and pepperoni, stir in some cooked crumbled bacon, cooked ground beef, or diced ham into the macaroni mixture. Each addition brings its own unique flavor profile and texture.
  • Veggie Extravaganza: Boost the nutritional content and add more layers of flavor by incorporating additional vegetables. Consider sautéed onions (if not already used with the peppers), sliced mushrooms, black olives, diced zucchini, or even a handful of fresh spinach (which will wilt down nicely) into the sausage and pepper mix. Just ensure to cook down any vegetables that release a lot of water to prevent a watery casserole.
  • Cheese Please! While mozzarella is a classic and reliable choice for the gooey topping, consider experimenting with a blend of cheeses for more complex flavors. Provolone adds a great stretch and mild flavor, shredded sharp cheddar provides a tangy kick, or a generous sprinkle of grated Parmesan cheese can add a salty, umami bite and a beautiful golden crust.
  • Different Sauces: The pizza sauce is central to the dish’s identity, but you can certainly play with its nuances. If you prefer a milder flavor, use a sweet marinara sauce. For a bolder, more complex taste, look for spicy pizza sauces, or simply add a dash of your favorite hot sauce or a pinch of red pepper flakes directly into your regular pizza sauce.
  • Herbaceous Touches: Fresh herbs can brighten up the flavors significantly. Freshly chopped basil, oregano, or parsley sprinkled generously over the top of the casserole after baking can add a vibrant, fresh finish. Alternatively, dried Italian seasoning can be mixed into the sauce for a more integrated herbal flavor throughout the dish.
  • Crunchy Topping: For an added textural contrast that’s deeply satisfying, create a crunchy topping. Mix about a quarter cup of Italian breadcrumbs with a tablespoon of melted butter and sprinkle this mixture evenly over the mozzarella cheese before baking. This will create a delightful, crispy, golden crust that adds another dimension to the casserole.

Serving Suggestions for Your Ultimate Comfort Dish

While the Macaroni and Cheese Pizza Casserole is undoubtedly a complete and hearty meal on its own, pairing it with a simple side dish can significantly elevate your dining experience and provide a welcome balance to the richness of the casserole. Here are a few ideas to perfectly complement your ultimate comfort dish:

  • Fresh Green Salad: A crisp, light green salad tossed with a zesty vinaigrette dressing is the perfect counterpoint to the rich and hearty casserole. The freshness, slight bitterness, and acidity of the salad will beautifully cut through the richness of the cheese and meat, cleansing the palate with each bite.
  • Garlic Bread or Cheesy Breadsticks: You can never go wrong with more bread, especially when it’s infused with garlic! Warm, crusty garlic bread or soft, cheesy breadsticks are excellent for soaking up any leftover savory sauce or stray bits of melted cheese, ensuring no deliciousness goes to waste.
  • Steamed Vegetables: For a simple yet nutritious addition, serve a side of steamed vegetables. Options like steamed broccoli, green beans, or asparagus can add a healthy and colorful element to your meal without requiring much additional effort or complicating the flavor profile.
  • Roasted Vegetables: Roasted vegetables offer a deeper flavor than steamed ones and pair wonderfully with the casserole. Consider roasting cherry tomatoes, additional bell peppers, or zucchini tossed with a little olive oil, salt, pepper, and Italian herbs. The caramelized edges and concentrated flavors will complement the casserole beautifully.

This Macaroni and Cheese Pizza Casserole truly embodies the spirit of comfort food reimagined. It’s simple enough for a busy weeknight yet exciting and flavorful enough to impress guests and become a staple at family gatherings. The harmonious blend of creamy pasta, savory Italian sausage, zesty pizza sauce, and perfectly melted cheese creates a dish that’s undeniably delicious, profoundly satisfying, and wonderfully versatile. So gather your ingredients, follow these straightforward steps, and prepare to enjoy a new family favorite that seamlessly combines the beloved best of macaroni and cheese with the irresistible charm of a classic pizza!